• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文学位 >Hand-held tonometer for transpalpebral intraocular pressure measurement.
【24h】

Hand-held tonometer for transpalpebral intraocular pressure measurement.

机译：手持式眼压计，用于经睑眼压测量。

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

This dissertation describes the development of a portable, hand-held tonometer for measurement of the intraocular pressure through the eyelid. The primary use of such device will be by people diagnosed with the eye disease glaucoma. Glaucoma is the second leading cause of blindness in the world and is asymptomatic to the patient in its early stages. This allows it to remain undiagnosed for prolonged periods, causing irreversible damage to the affected person's vision. Elevated intraocular pressure is the main risk factor associated with the development of glaucoma, and is currently the only symptom that is treatable for the slowing down or stopping of the progression to blindness caused by the disease. The effectiveness of the medications or procedures aimed at reducing the pressure to below risk levels is currently monitored through visits to the ophthalmologists' offices, which makes the frequent monitoring of the pressure inconvenient, expensive and sometimes impossible. Due to the variation of the pressure throughout the day and during different activities or food and beverage intake, the portability of the device is important in order to allow the user to carry it with them and take measurements as frequent as needed. The option to perform the measurement through the eyelid avoids direct contact with the eye, eliminating possible discomfort, the use of anesthetics, and the risk of contamination.;Several designs and measuring concepts are evaluated using a custom made pressure regulation system. A series of prototypes have been built and tested and the results are reported in the respective sections of the dissertation. The final concept selected for the measurement technique was based on multiple force probe indentation and a custom MEMS-based force sensor for it was designed and tested.;The main contributions of this dissertation are the design, fabrication and test of the prototype devices and the MEMS force sensors. The obtained results and experience described here can serve as a platform for further optimization and improvement of the device, and eventual development of a prototype capable of performing clinical research studies and passing FDA approval for home and clinical use.
机译：本论文描述了便携式手持眼压计的发展，该眼压计用于测量通过眼睑的眼内压。这种设备的主要用途是被诊断为患有眼部疾病的青光眼。青光眼是世界上第二大失明的主要原因，在早期阶段对患者无症状。这使得它可以长时间不被诊断，从而对受影响的人的视力造成不可挽回的损害。眼内压升高是与青光眼发展有关的主要危险因素，并且目前是可用于减缓或停止由该疾病引起的失明进程的唯一症状。当前，通过拜访眼科医生办公室来监测旨在将压力降低到低于风险水平的药物或程序的有效性，这使得对压力的频繁监视不便，昂贵并且有时是不可能的。由于一天中以及在不同活动或食物和饮料摄入期间压力的变化，设备的便携性很重要，以便允许用户随身携带并根据需要进行频繁的测量。通过眼睑执行测量的选项可以避免与眼睛直接接触，从而消除可能的不适感，使用麻醉剂和污染的风险。;使用定制的压力调节系统评估了几种设计和测量概念。已经构建并测试了一系列原型，结果在论文的各个部分中进行了报告。为测量技术选择的最终概念是基于多个力探针压痕，并针对其设计和测试了基于MEMS的定制力传感器。本论文的主要贡献在于原型设备和传感器的设计，制造和测试。 MEMS力传感器。这里描述的获得的结果和经验可以用作进一步优化和改进设备的平台，并最终开发出能够进行临床研究并通过FDA批准用于家庭和临床用途的原型。

著录项

  • 作者

    Polyzoev, Vasco Djovaniev.;

  • 作者单位

    The University of Arizona.;

  • 授予单位 The University of Arizona.;
  • 学科 Engineering Mechanical.;Biophysics Biomechanics.
  • 学位 Ph.D.
  • 年度 2011
  • 页码 135 p.
  • 总页数 135
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号