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The diet study in lactating women: A Mediterranean-style diet intervention and its effects on postpartum weight loss, body composition and select biomarkers of inflammation.

机译:哺乳期妇女的饮食研究:地中海式饮食干预及其对产后体重减轻,身体成分和炎症选择生物标志物的影响。

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摘要

Obesity-related diseases account for the majority of morbidity and mortality in U.S. adults. An estimated 4 million women in the United States deliver an infant annually, of which approximately 34% are overweight/obese prior to pregnancy. More than 30% of these women gain weight that exceeds the IOM's recommendations; increasing their risk of postpartum weight retention and possibly increasing their risk of greater weight gain and retention over time. This research sought to test the efficacy of a traditional MED diet for 4-months on weight loss/control and biomarkers of inflammation in breastfeeding women compared to women randomized to the USDA's MyPyramid diet for Pregnancy and Breastfeeding (control diet). At baseline, the women (N=129) were 29.7+/-4.6 years, overweight (BMI: 27.2+/-4.9 kg/m2), and primarily non-Hispanic white (75.2%). The majority of women were exclusively breastfeeding (73.6%) and a mean 17.5 weeks postpartum. Adherence to the MED diet was evaluated via calculation of the MED diet score from validated FFQs administered pre- and post- the diet intervention. Anthropometric measurements (body weight, body fat, and waist and hip circumference) and biosamples (blood, urine, and breast milk) were collected at baseline and 4-months (diet completion). Biomarkers of inflammation (IL-6 and TNF-alpha) were assessed via standard ELISA kits. The MED diet score was increased by 0.68+/-2.74 and 0.27+/-1.57 for the MED and control group, respectively. Increases in fish and dairy intake and a decrease in meat/poultry intake were significantly different between diet groups (P0.05). Participants in both diet groups demonstrated significant (P=0.002) reductions in all anthropometric measurements; no significant between group differences were shown. A significant decrease in TNF-alpha, but not IL-6, was demonstrated in both diet groups. There were no significant between group differences. Both the MED diet and the USDA's MyPyramid diet were effective in reducing anthropometric measurements and inflammation in postpartum breastfeeding women.
机译:肥胖症相关疾病占美国成年人发病率和死亡率的大部分。在美国,估计每年有400万妇女分娩婴儿,其中约34%在怀孕前超重/肥胖。这些妇女中超过30%的体重超过了IOM的建议;增加他们产后体重保持的风险,并可能随着时间的推移增加体重增加和保持的风险。这项研究旨在测试传统MED饮食4个月对母乳喂养妇女的体重减轻/控制和炎症生物标志物的功效,与随机分配给USDA的MyPyramid妊娠和母乳喂养饮食(对照饮食)的妇女相比。在基线时,女性(N = 129)为29.7 +/- 4.6岁,超重(BMI:27.2 +/- 4.9 kg / m2),主要为非西班牙裔白人(75.2%)。大多数妇女仅接受母乳喂养(73.6%),平均在产后17.5周。通过计算饮食干预前后经验证的FFQ的MED饮食评分来评估对MED饮食的依从性。在基线和4个月(饮食完成)时收集人体测量值(体重,体脂肪以及腰围和臀围)和生物样本(血液,尿液和母乳)。通过标准ELISA试剂盒评估炎症的生物标志物(IL-6和TNF-α)。 MED组和对照组的MED饮食评分分别提高了0.68 +/- 2.74和0.27 +/- 1.57。饮食组之间鱼和奶制品摄入量的增加以及肉/禽类摄入量的减少有显着差异(P <0.05)。两种饮食组的参与者在所有人体测量学中均显示出显着(P = 0.002)的减少。组间差异无显着性。在两个饮食组中,TNF-α均显着降低,但IL-6并未显着降低。组间差异无统计学意义。 MED饮食和USDA的MyPyramid饮食均可有效减少产后母乳喂养妇女的人体测量和炎症。

著录项

  • 作者

    Stendell-Hollis, Nicole R.;

  • 作者单位

    The University of Arizona.;

  • 授予单位 The University of Arizona.;
  • 学科 Womens Studies.;Health Sciences Nutrition.
  • 学位 Ph.D.
  • 年度 2011
  • 页码 123 p.
  • 总页数 123
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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