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Computational study of electromagnetic wave induced by mobilephones on brain tissues and its biological implications.

机译：手机在脑组织上诱发的电磁波的计算研究及其生物学意义。

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摘要

The mobile devices, mobile phones in particular, have become an integral part of today's society with billions of users worldwide. Despite much research efforts have been done over decades, possible adverse effects of radiofrequency (RF) radiation on human health are still unclear. Although some research results show that there is elevated risk of causing cancer in human brains, other studies lead to inconclusive results. One major concern is whether brain tumors will be induced by mobile phone's RF radiation and other sources of electromagnetic waves around us. The objective of this study is to develop an effective computational method to investigate and characterize the spatial distribution of RF energy absorbed by different parts of the brain, which caused by use the mobile phone in a close distance, and study its biological implications. In this thesis, we use mathematical models and computer simulation to generate 3D distributions of the specific absorption rate (SAR) induced by mobile phone use in human head models. One digital brain model is developed based on MRI scan data, and the other is an IEEE phantom for benchmark tests. A generic phone model is also developed to study interaction of RF radiation and the brains. The Finite Difference Time Domain (FDTD) method is used to solve Maxwell equations that govern the biophysical response in the brain tissues. SAR distributions due to exposure to an electromagnetic field from mobile phones are estimated based on the solution to the Maxwell equations. Using 3-D SAR distributions, which are quantitative measures of energy deposited in the brain tissues in specific locations, we may determine most susceptible (stressful) regions that may be affected by the use of cellular phones. We hypothesize that the brain cells are affected by the long-term exposure of radiation that imposes stressful conditions resulting in alteration or mutations of the DNA sequences in brain cells. Finally, biological experiments are suggested to test our hypothesis using heat shock proteins (e.g. HSP27) as biomarkers to quantify long-term EM effects.
机译：移动设备（尤其是移动电话）已成为当今社会不可或缺的一部分，全球数十亿用户。尽管数十年来已进行了大量研究工作，但射频（RF）辐射对人体健康的可能不利影响仍不清楚。尽管一些研究结果表明，人脑中罹患癌症的风险增加，但其他研究仍未得出结论。一个主要的问题是，手机周围的射频辐射和其他电磁波源是否会诱发脑瘤。这项研究的目的是开发一种有效的计算方法，以研究和表征近距离使用手机引起的大脑不同部位吸收的射频能量的空间分布，并研究其生物学意义。在本文中，我们使用数学模型和计算机模拟来生成人头模型中手机使用引起的比吸收率（SAR）的3D分布。一种基于MRI扫描数据的数字大脑模型，另一种是用于基准测试的IEEE幻像。还开发了通用电话模型来研究RF辐射与大脑的相互作用。时域有限差分（FDTD）方法用于求解控制大脑组织中生物物理响应的麦克斯韦方程。基于麦克斯韦方程的解，估算了由于手机电磁场引起的SAR分布。使用3-D SAR分布（这是对特定位置在脑组织中沉积的能量的定量度量），我们可以确定可能受到手机使用影响的最敏感（压力）区域。我们假设大脑细胞受到长期照射的辐射的影响，该辐射会施加压力条件，从而导致大脑细胞中DNA序列发生改变或突变。最后，建议进行生物学实验以验证我们的假设，即使用热激蛋白（例如HSP27）作为生物标记来量化长期EM效应。

著录项

  • 作者

    Gogineni, Swandana.;

  • 作者单位

    The University of Texas at San Antonio.;

  • 授予单位 The University of Texas at San Antonio.;
  • 学科 Biology Neuroscience.;Biophysics General.;Engineering Mechanical.;Biology Cell.
  • 学位 M.S.
  • 年度 2010
  • 页码 85 p.
  • 总页数 85
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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