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Bioavailability and antioxidant protection of lycopene from watermelon.

机译：番茄红素对西瓜的生物利用度和抗氧化保护作用。

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摘要

Watermelons are a rich source of the carotenoid lycopene. Researchers have reported that lycopene acts as an antioxidant in vitro by providing protection to human cells against oxygen and peroxy radicals. The objectives of this study were to evaluate the antioxidant protection provided to subjects by 20 or 40 mg/day of lycopene from watermelon. Twelve healthy, non-smoking adults (six men and six women) were given three treatments of a control, 20 and 40 mg/day of lycopene from watermelon juice for three weeks in a nineteen-week crossover study. Each treatment period was followed by a four-week lycopene depletion washout period. Plasma was analyzed for malondialdehyde formation products (MDA), plasma glutathione peroxidase (GPX) and ferric reducing ability of plasma (FRAP). Lycopene was readily absorbed by the subjects from the non-heat processed watermelon juice, but there was not a linear dose response. There were no significant differences in MDA, GPX or FRAP levels with either dosage level of lycopene or between treatments and controls. There were gender differences in MDA levels with women having higher MDA levels compared to men. However, the inclusion of lycopene to the diet in the form of watermelon juice did not affect the antioxidant status of healthy subjects.
机译：西瓜是类胡萝卜素番茄红素的丰富来源。研究人员报告说，番茄红素通过为人体细胞提供抗氧和过氧自由基的保护作用，成为体外的抗氧化剂。这项研究的目的是评估来自西瓜的20或40毫克/天的番茄红素对受试者的抗氧化保护作用。在十九周的交叉研究中，对十二名健康，不吸烟的成年人（六名男性和六名女性）进行了三种治疗，分别是对照，西瓜汁中番茄红素的含量为20和40毫克/天/天，持续三周。每个治疗期之后是四周的番茄红素消耗清除期。分析血浆中的丙二醛形成产物（MDA），血浆谷胱甘肽过氧化物酶（GPX）和血浆铁还原能力（FRAP）。番茄红素很容易从未经热处理的西瓜汁中吸收，但是没有线性剂量反应。番茄红素的剂量水平或治疗与对照之间的MDA，GPX或FRAP水平无显着差异。 MDA水平存在性别差异，女性的MDA水平高于男性。但是，将番茄红素以西瓜汁的形式添加到饮食中不会影响健康受试者的抗氧化状态。

著录项

  • 作者

    Collins, Julie Kay.;

  • 作者单位

    Oklahoma State University.;

  • 授予单位 Oklahoma State University.;
  • 学科 Health Sciences Nutrition.
  • 学位 Ph.D.
  • 年度 2003
  • 页码 99 p.
  • 总页数 99
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 预防医学、卫生学;
  • 关键词

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