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Evaluation of methicillin-resistant Staphylococcus aureus and the characterization of Staphylococcus pseudintermedius in dogs and cats.

机译：耐甲氧西林金黄色葡萄球菌的评价和狗和猫中伪葡萄球菌的特征。

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摘要

This thesis is an investigation of methicillin-resistant Staphylococcus aureus (MRSA) infections and the microbiological characterization of Staphylococcus pseudintermedius infections in dogs and cats.;A retrospective case-control study was conducted to compare clinical presentations, infection types, clinical outcomes, and determine risk factors associated with MRSA, compared to methicillin-susceptible Staphylococcus aureus (MSSA) infections. The administrations of antimicrobials, specifically fluoroquinolones, within 90 days prior to admission, were significant risk factors for the development of MRSA infections.;In a second investigation, 85.7% of phenotypically identified S. intermedius isolates were molecularly identified as S. pseudintermedius. No isolates were molecularly identified as S. intermedius. A prevalence of 17.7% and 61.5%, for the mecA and S. intermedius exfoliative toxin genes, respectively, were observed in S. pseudintermedius isolates.;In a third investigation, inducible clindamycin-resistance was detected in 16.7% of MRSA and 0% of S. pseudintermedius isolates. The prevalence of erm(A), erm(B), and erm(C) genes were investigated in all isolates.
机译：本文是对耐甲氧西林的金黄色葡萄球菌（MRSA）感染和猫和狗中金黄色葡萄球菌感染的微生物学特征的研究;进行了一项回顾性病例对照研究，以比较临床表现，感染类型，临床结果并确定与甲氧西林敏感的金黄色葡萄球菌（MSSA）感染相比，与MRSA相关的危险因素。入院前90天内服用抗微生物药，特别是氟喹诺酮类药物是发生MRSA感染的重要危险因素。；在第二项研究中，从表型上鉴定出的中间链球菌分离物在分子上被鉴定为假性链球菌，占85.7％。没有分离物被分子鉴定为中间链球菌。在pseudintermedius分离株中，mecA和中间人链球菌剥脱毒素基因的患病率分别为17.7％和61.5％；在第三次调查中，在16.7％的MRSA和0％的细菌中检测到诱导性克林霉素耐药性pseudintermedius分离株。在所有分离物中研究了erm（A），erm（B）和erm（C）基因的患病率。

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  • 作者

    Faires, Meredith C.;

  • 作者单位

    University of Guelph (Canada).;

  • 授予单位 University of Guelph (Canada).;
  • 学科 Agriculture Animal Pathology.;Biology Veterinary Science.
  • 学位 M.Sc.
  • 年度 2009
  • 页码 171 p.
  • 总页数 171
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 动物医学（兽医学）;动物学;
  • 关键词

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