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Use of active immunization against somatostatin in the manipulation of the ruminant endocrine system.

机译：针对生长抑素的主动免疫在反刍动物内分泌系统中的应用。

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Three experiments were conducted to investigate the effects of active immunization against somatostatin (SS) on, (1) the lactational performance of ruminants, (2) growth hormone (GH) secretion and metabolism and (3) the relationship between immunization, plane of nutrition, GH and somatomedin C (SmC) metabolism. In experiment (Exp.) 1, 12 lactating Nubian dairy goats (47 kg) were divided between immunized (I) (biweekly injections of SS-human serum globulin conjugate for 16 wk) and control (C) groups, which received globulin alone. Antibody titer, milk yield, constituent secretion and feed efficiency were measured. Immunization against SS did not affect milk or milk constituent yield, feed efficiency, temporal or GRF-challenged GH levels. In Exp. 2, the response of I and C steers which had been previously immunized for 12 wk, as in Exp. 1, to graded intravenous doses of GRF (0, 25, 50 or 100

机译：进行了三个实验以研究针对生长抑素（SS）的主动免疫对（1）反刍动物的泌乳性能，（2）生长激素（GH）分泌和代谢以及（3）免疫，营养面之间的关系的影响，GH和生长抑素C（SmC）代谢。在实验（实验）1中，将12头哺乳期的努比亚奶山羊（47公斤）分为免疫组（I）（每两周注射SS-人血清球蛋白缀合物16周）和对照组（C），对照组分别接受球蛋白。测量抗体滴度，产奶量，成分分泌和饲料效率。接种SS疫苗不会影响牛奶或牛奶成分的产量，饲料效率，时间或GRF挑战的GH水平。在实验中如图2所示，先前已免疫12周的I和C转向的反应如实验2所示。 1，GRF分级静脉注射剂量（0、25、50或100

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作者
Kenison, Dale Christopher.;
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Texas A&M University.;

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授予单位 Texas A&M University.;
学科 Agriculture Animal Culture and Nutrition.
学位 Ph.D.
年度 1987
页码 107 p.
总页数 107
原文格式 PDF
正文语种 eng
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专利

1. Effects of active immunization against somatostatin or somatostatin analogues on milk production in rats. [J] . Yi ImGap, Lim DaeSung, Kim JaeYoung, Nutrition Research . 1999,第7期

机译：生长抑素或生长抑素类似物主动免疫对大鼠产奶的影响。
2. Effect of active immunization against a recombinant mouse granulocyte-macrophage colony-stimulating factor/somatostatin fusion protein on the growth of mice [J] . Wu Bingbing, Qi Ruili, Li Bin, Molecular biology reports . 2012,第6期

机译：重组小鼠粒细胞-巨噬细胞集落刺激因子/生长抑素融合蛋白主动免疫对小鼠生长的影响
3. Hormonal response of male dairy calves infused with growth hormone-releasing factor and/or actively immunized against somatostatin. [J] . Roy N, Pelletier G, Farmer C, Acta Agriculturae Scandinavica. Section A, Animal Science . 1999,第1期

机译：注入生长激素释放因子和/或主动免疫生长抑素的雄性牛犊的激素反应。
4. The effect of active immunization against somatostatin on growth and growth hormone gene expression in growing Huzhou sheep [C] . . 2005

机译：生长抑素主动免疫对湖州绵羊生长和生长激素基因表达的影响
5. Design and synthesis of biologically active peptidomimetic somatostatin analogs [D] . Moore, Sandra Blaj 2004

机译：具有生物活性的拟肽生长抑素类似物的设计与合成
6. Somatostatin-receptor 2 (sst2)-mediated effects of endogenous somatostatin on exocrine and endocrine secretion of the rat stomach [O] . Vidar Fykse, David H Coy, Helge Lyder Waldum, 2005

机译：生长抑素受体2（sst2）介导的内源性生长抑素对大鼠胃内分泌和内分泌的影响
7. Active immunization against somatostatin increases milk yield in goats. [O] . G.J. Garssen, A.M.A.W. Welling, G.S.G. Spencer 1987

机译：对生长抑素的主动免疫增加山羊牛奶产量。

Use of active immunization against somatostatin in the manipulation of the ruminant endocrine system.

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