Objective In order to supply the theoretic proof and reference for optimal designing vaneless centrifugal pump, the relationship between the structure of vaneless centrifugal pump and key parameters in extracorporeal circulation were explored. Methods The calculation model of vaneless centrifugal pump was simulated and validated in terms of key performance parameters such as pump- s structure, rotation speed, flow rate, flow state in pump, and prime volume by the method of computational fluid dynamics (CFD) . Results The centrifugal pump with two layer of impeller was more powerful, however with more prime volume in pumping blood, than that with one in the same rotation speed. The pump with a smaller pipe diameter was favorable for changing the flow rate. The structure and rotation speed greatly affected the velocity distribution in the pump. Conclusions The structure and rotation speed of vaneless centrifugal pump make a great impact on the control strategies of flow, velocity distribution and prime volume.%目的 探讨无叶片离心泵结构和体外循环关键参数之间的关系,为无叶片离心泵的优化设计提供理论依据和实践参考.方法 采用计算流体动力学(computational fluid dynamics,CFD)方法对无叶片离心泵进行数值模拟,分析离心泵的结构和转速与血液流量、泵内流动状态、预充量之间的关系.结果 叶轮与蜗壳之间距离一定时,两层叶轮结构比一层叶轮结构驱动血液能力强,但是预充量大;进出口导管直径小,有利于调节流量;泵体结构和叶轮转速影响泵内的血液速度分布,从而会对血液造成不同程度的破坏.结论 无叶片离心泵结构和叶轮转速对体外循环流量的控制、泵内血液速度分布、预充量有很大影响.
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