本文以N-(3-溴丙基)邻苯二甲酰亚胺合成为模板反应,研究了相转移催化无溶剂合成N-(ω-溴烷基)邻苯二甲酰亚胺的影响因素,实验证实相转移催化剂及其用量、催化剂K2CO3的用量等对反应的影响明显,得到N-(3-溴丙基)邻苯二甲酰亚胺的优化合成条件为:反应物配比为PA∶C3 Br2∶K2CO3∶TBAB=1∶2∶4∶0.2,反应温度80℃,反应时间1h,N-(3-溴丙基)邻苯二甲酰亚胺产率为92％.在相同反应条件下,N-(ω-溴烷基)邻苯二甲酰亚胺的产率随α,ω-二溴烷烃的烷基链长度增加而降低.%Derivation of calixarenes on the upper/lower rims with ligands was the main route to improve their complexation and selective capabilities for separating actinides and lanthanides.N-(ω-bromoalkyl) phthalimide was an important intermediate in the synthesis procees of calixarene derivatives.In this article,using N-(ω-bromoalkyl) phthalimide as the template,the relation between the yield of N-(ω-bromoalkyl)phthalimide and reaction conditions were investigated.The yield of N-(ω-bromoalkyl)phthalimide was above 92％ through optimizing the reaction conditions.The type of the phase transfer catalysts and their amounts and the amounts of K2CO3 were the key influence factors in the N-alkyhtion of phthalimide reaction by the solvent-frse way.In eddition,the increasing of the length of chains would decrease the yield of N-(ω-bromoalkyl) phthalimide under the same reaction conditions.
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