Objective To study the detection value of blood lipid for the heart function of patients with chronic heart failure. Methods 43 patients with chronic heart failure in the TCM Hospital of Chengde City from May 2009 to December 2011 were selected as observation group, and 43 healthy persons at the same time were selected as control group, then the blood lipid and cardiac reserve index, ejection fraction, high sensitivity C reactive protein (hs—CRP), N end B type natriuretic peptide (NT—proBNP) of two groups were studied and compared. Results The total cholesterol (TC), triglyceride (TG), high density lipoprolein (HDL—C), low density lipoprolein (LDL—C), Apolipoprotein A (Apo—A) and cardiac reserve index, ejection fraction of observation group were all lower than those of control group, hs—CRP, NT—proBNP and lipoprolein a (LP—a) were all higher than those of control group, and the higher the heart function stage, the bigger the differences which were compared to those of control group, there were all significant differences (all P < 0.05). Conclusion The detection of blood lipid for the heart function of patients with chronic heart failure has higher clinical value, the investigation of cardiac reserve index, ejection fraction, hs—CRP, NT—proBNP can reflect the value from the side.%目的 探讨慢性心力衰竭患者血脂水平检测对心功能的诊断价值.方法 选取2009年5月～2011年12月于河北省承德市中医院进行治疗的43例慢性心力衰竭患者为观察组,同期的43名健康人为对照组,两组人员的血脂及心脏储备指数、射血分数、超敏C反应蛋白(hs-CRP)、N末端B型钠尿肽原(NT-proBNP)水平进行研究及比较.结果 观察组的总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白A(Apo-A)及心脏储备指数、射血分数均低于对照组,hs-CRP、NT-proBNP、脂蛋白α(LP-α)水平均高于对照组,而心功能分级越高则上述指标较对照组的差异越大,射血分数越低者差异越大,差异均有统计学意义(均P ＜ 0.05).结论 慢性心力衰竭患者血脂水平检测对心功能的诊断有较高的临床价值,对于心脏储备指数、射血分数、hs-CRP、NT-proBNP水平的了解可以从一个侧面反映这种价值.
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