Objective To analyze the distribution and drug sensitivity of pathogens in the pus of surgical wound infection after appendectomy, in order to provide a sound basis for antibiotics application. Methods Bacterial culture and drug sensitivity test were performed in the pus of surgical wound infection after appendectomy in 49 cases. The results were analyzed statistically. Results Pathogens in 36 cases were detected, and 40 strains were isolated from the pus of surgical wound infection, among them 4 cases suffered with mixed infection of two bacteria. The top three bacteria was Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa, accounting for 65.0%, 12.5% and 7.5% of the total number of bacteria respectively. The sensitive rates of Escherichia coli to Amikacin, Cefoxitin, Imipenem and Meropenem were 96.1%, 88.5%, 100.0% and 100.0%. Conclusion Escherichia coli is the major pathogen in the pus of surgical wound infection after appendectomy. The recommended antibiotics are Amikacin plus Metronidazole or Cefoxitin plus Metronidazole for the patients with surgical wound infection after appendectomy.%目的 分析阑尾炎术后切口感染脓液中的病原菌分布情况及药物敏感性,为临床选择抗菌药物提供参考.方法 对我院49例阑尾炎术后切口感染的脓液进行细菌培养和药物敏感试验,对结果进行统计分析.结果 49例脓液标本有36例检出细菌,分离到细菌40株,有4例为两种细菌混合感染;排在前3位的细菌依次为大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌,分别占检出细菌总数的65.0%、12.5%、7.5%.大肠埃希菌对阿米卡星、头孢西丁、亚胺培南、美罗培南的敏感率分别为96.1%、88.5%、100.0%和100.0%.结论 大肠埃希菌为阑尾炎术后切口感染的主要致病菌,对切口感染患者临床推荐使用头孢西丁加甲硝唑或阿米卡星加甲硝唑.
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