Objective: To compare the data of clinical presentations, laboratory and auxiliary examinations of viral en cephalitis in adults with those in children. Methods: The data of the in-patients who were diagnosed as viral encephalitis were collected in China-Japan Friendship Hospital from February 1993 to February 2003, and were retrospectively analyzed. Results: Among the total of 55 patients with viral encephalitis, 22 patients were children, and 33 patients were adults, the incidences of the convulsion, conscious disturbance and diarrhea in children with viral encephalitis were significant higher than those in adults (ρ=0.012 2, ρ=0.007 9, ρ=0.070 3). The incidence of the headache in children with viral encephalitis was lower than that in adults (ρ=0.001 3). Other signs and results such as Babinski's reflex, laboratory and auxiliary examinations in this study were not significant difference (ρ＞0.05). Conclusion: There are significant differences of some symptoms of viral encephalitis between adult group and children group, but the results of laboratory and auxiliary examinations are not difference between the two groups, indicates that the viral encephalitis in both groups shares the same' mechanism of the pathophysiology.%目的:比较成年和儿童病毒性脑炎的临床表现、实验室和辅助检查结果的异同.方法:收集1993年2月～2003年2月在中日友好医院住院的55例诊断为病毒性脑炎的成人和儿童患者,对其临床和实验室辅助检查结果进行回顾性分析.结果:55例患者中,儿童组22例,成人组33例,儿童组病毒性脑炎患者临床症状中的抽搐、意识障碍和腹泻的发生率明显高于成人组(P=0.0122、P=0.0079、P=0.0703);而头痛的发生率则明显低于成人组(P=0.0013).其他临床体征如巴宾斯基征等、实验室和辅助检查结果差异无统计学意义(P>0.05).结论:儿童和成年病毒性脑炎患者的部分临床症状不同,而实验室和辅助检查结果多无显著区别,提示成人和儿童发生病毒性脑炎的病理生理机制相同.
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