A number of studies indicate that the glutamate signal transduction system is closely related with the oc-currence of mental disorders. A glutamate pathway in the central nervous system, especially in the hippocampus neu-ron, plays an important role in neuron growth and synaptic plasticity. In this paper, the relationship of glutamate sig-naling pathway in the hippocampus and the incidence of schizophrenia is reviewed by exploring the structure and function of the hippocampus in order to better understand the pathogenesis of schizophrenia.%多项研究表明谷氨酸信号转导系统与精神心理疾病的发生有着密切的关系。谷氨酸通路在中枢神经系统尤其是在海马区对神经元的生长和突触可塑性发挥着重要的作用。本文从海马的结构和功能出发，对海马内的谷氨酸信号转导通路及与精神分裂症的发生进行综述，以更深入地了解海马认知功能及精神分裂症的发生机制。
展开▼
