目的：探讨支气管肺泡灌洗术、纤维支气管镜(纤支镜)刷片及痰脱落细胞学联合检测在肺癌诊断中的应用价值。方法200例肺癌患者采用支气管肺泡灌洗术、纤支镜刷片及痰脱落细胞学检测，比较并探讨三种方法及联合检测的诊断价值。结果200例患者采用支气管肺泡灌洗术、纤支镜刷片、痰脱落细胞学检测及三者联合检测，其中支气管肺泡灌洗术、纤支镜刷片及痰脱落细胞学检测阳性例数分别为44、48、18例，支气管肺泡灌洗术阳性率为22%，纤支镜刷片阳性率为24%，痰脱落细胞学阳性率为9%，其中痰脱落细胞学检测阳性率最低，与其他两种检测方法比较差异有统计学意义(P<0.05)。联合检测阳性例数68例，联合检测阳性率为34%，与单一检测比较差异有统计学意义(P<0.05)。结论支气管肺泡灌洗术、纤支镜刷片及痰脱落细胞学联合检测有助于肺癌的诊断。%Objective To investigate application value of bronchoalveolar lavage, bronchofiberscope brush smear and sputum exfoliocytology in joint detection for diagnosis of lung cancer. Methods A total of 200 patients received bronchoalveolar lavage, bronchofiberscope brush smear and sputum exfoliocytology for detection. Comparison and investigation were made on diagnostic value by the three measures and joint detection. Results All the 200 patients received bronchoalveolar lavage, bronchofiberscope brush smear, sputum exfoliocytology and joint detection by the three measures. Positive cases detected by bronchoalveolar lavage, bronchofiberscope brush smear and sputum exfoliocytology were respectively 44, 48 and 18 cases. Bronchoalveolar lavage showed positive rate as 22%, which was 24% by bronchofiberscope brush smear and 9% by sputum exfoliocytology, and sputum exfoliocytology had the lowest positive rate. Their difference had statistical significance (P<0.05). Joint detection showed 68 positive cases, with positive rate as 34%, and its difference from single detection had statistical significance compared with other two detection methods (P<0.05). Conclusion Joint detection by bronchoalveolar lavage, bronchofiberscope brush smear and sputum exfoliocytology is helpful for diagnosis of lung cancer.
展开▼
