目的：探讨新生儿宫内感染与母围生期相关因素的关系。方法：对2014年1-3月在笔者所在医院分娩的5024例活产新生儿的临床资料(其中377例诊断为宫内感染)进行回顾性分析，研究母产前发热、胎膜早破、产前血象、中性粒细胞计数、CRP及生殖道分泌物培养等因素与宫内感染的关系。结果：母产前发热、胎膜早破、产前血象异常、中性粒细胞计数升高、CRP升高、生殖道分泌物培养阳性、胎盘病检阳性等六项因素明显增加新生儿宫内感染的风险。结论：对于母围生期上述六项因素有异常的新生儿，应密切观察临床症状，完善实验室检查，必要时使用抗生素，做到积极治疗，最大程度降低围产儿死亡率。%Objective:To investigate the correlation between neonatal intrauterine infection and related factors in perinatal stage.Method:Retrospective analysis of totally 5024 live birth babies (including 377 babies with intrauterine infection) were made to observe the correlation between neonatal intrauterine infection and the six factors of prenatal fever, premature rupture of membranes,white blood cell count,C-reactive protein and cultivation of genital secretions.Result:The six factors of prenatal fever,premature rupture of membranes,white blood cell count,C-reactive protein and cultivation of genital secretions markedly increased the risk of neonatal intrauterine infection.Conclusion:We should pay close attention to the babies with the above abnormal factors,complete laboratory examinations,and give antibiotics on occasion to furthest reduce mortality rate of neonates.
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