Objective To investigate the quality of life in patients with chronic prostatitis (CP) and analyze its influencing factors. Methods From May 2010 to July 2011 , a total of 283 outpatients with chronic'prostatitis aged 20 to 50 years were consecutively enrolled in this study. Anonymous questionnaires were used, in which there were 29 items including patient's age, marital status, occupation, educational background, comorbidities, sexual frequency, income, cigarette smoking, alcohol consumption, disease course, score of the National Institute of the Health Chronic Prostatitis Symptom Index (NIH-CPSI), and Medical Outcomes Study Short-form 36 (MOS SF-36). Eleven possible influencing factors for prostatitis were analyzed by using the conditional univariate and multivariate linear regression methods to identify finally the possible influencing factors. Results 283 valid questionnaires were collected. The quality of life of CP patients in all the dimensions of SF -36 lowered. Symptom scores of NIH-CPSI were negatively correlative to PF, RP, GH, VT, SF, RE, MH(r=-0.813, r=-0.395, r=0.708, r=-0.828, r=-0.433, r=-0.642, r=-0.732, r=-0.855, P<0.01). Pain scores of NIH-CPSI was negatively correlative to BP (P<0.01). Conclusion Chronic prostatitis has a significant impact on patients' QOL. The intensity of the impact is associated with NIH-CPSI, age, occupation, comorbidities, income, disease course, etc. The SF-36 scales are applicable for measuring the quality of life of patients with CP. It is advisable to use SF-36 with NIH-CPSI to assess patients with CP.%目的 分析慢性前列腺炎(CP)对患者生活质量的影响,探讨其影响因素.方法2010年5月至2011年7月期间,泌尿外科门诊CP患者283例,无记名填写调查表,内容包括美国国立卫生研究院慢性前列腺炎症状积分指数(NIH-CPSI),生活质量评分(SF-36中文版),年龄、婚姻、职业、文化水平、合并慢性疾病情况、性生活频数、经济收入、吸烟、饮酒、病程的问卷调查.结果 与对照组相比,CP患者在SF-36量表所有领域的积分均有下降,P值均＜0.01.NIH-CPSI包括疼痛或不适平均评分,排尿评分和生活质量评分,前两项为症状评分(NIH-CPSI1,2),与SF-36得分负相关,P值均＜0.01.结论CP对患者的生存质量的影响,不仅仅局限于精神心理、性功能方面,而是对患者生活质量多个方面如:生理功能、生理职能、社会功能都有不同程度的影响.但对不同方面的影响程度不相同,提示在对CP患者进行干预治疗时应全面而有重点的考虑到CP对患者生活质量的影响.建议在应用NIH-CPSI评估CP患者生存质量时可联合应用SF-36对CP.
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