Objective To study the correlation of arterial elasticity with the levels of serum uric acid and blood lipid in middle and elderly male population.Methods A total of 279 male were enrolledand physical,biochemical and arterial elasticity tests were performed.Based on the pulse wave velocity(PWV),these were divided into two groups in-cluding non-arteriosclerosis group of 138 cases and arteriosclerosis group of 141 cases.Then we analyzed the correlation of arterial elasticity with serum uric acid and blood lipid levels.Results Compared with the non-arteriosclerosis control group,the serum levels of UA[(409.38 ±92.78)mmol/L VS.(433.84 ±93.43)mmol/L]and TG[(1.64 ±0.83) mmol/L VS.(2.26 ±1.37)mmol/L]were significantly elevated in arteriosclerosis group(P<0.05 or P<0.01), while there was no significant difference on the levels of LDL,HDL and TCh between the two groups.Pearson correlation analysis showed that there was a positive correlation of PWV with age,waist circumference and TG(r=0.169-0.439, P<0.05 or P<0.01).Conclusion TG,hyperuricemia,obesity,hypertension and abnormal blood glucose are risk fac-tors for atherosclerosis in middle-aged and elderly men.%目的 研究中老年男性动脉弹性与血清尿酸及血脂水平的相关性.方法 选取男性体检者279例,进行体格、生化及动脉弹性检查,根据脉搏波传导速度(PWV)测定分为动脉硬化组138例,非动脉硬化组141例,分析动脉弹性与血清尿酸、血脂水平之间的相关性.结果 与非动脉硬化对照组比较,动脉硬化组血清尿酸[(409.38 ±92.78)mmol/L比(433.84 ±93.43)mmol/L]、三酰甘油(TG)[(1.64 ±0.83)mmol/L比(2.26 ± 1.37)mmol/L]水平显著升高(P<0.05或P<0.01),而低密度脂蛋白(LDL)、高密度脂蛋白(HDL)及总胆固醇(TCH)水平差异无统计学意义.Pearson相关性分析显示,年龄、腰围、TG与肱-踝脉搏波传导速度存在明显的正相关(r=0.169~0.439,P<0.05或 P<0.01).结论 TG水平与动脉硬化密切相关,同时高尿酸血症、肥胖、高血压及血糖异常是中老年男性动脉硬化的危险因素.
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