Objective To investigate the effects of monopolar coagulation on ovarian function during laparo -scopic ovarian cystectomy .Methods One hundred and fifty cases of patients with unilateral ovarian cysts who were admitted to our hospital from June 2009 to June 2012 were randomly divided into three groups according to balloting method,namely ultrasonic scalpel group(n=50),endoscopic suture group(n=50) and unipolar coagulation group(n=50).The menstrual changes,the occurrence of menopause syndrome and hormone (E2,FSH) levels before surgery, after 2 months'and 4 months'surgery were compared.Results (1)The menstrual changes after surgery and monopo-lar coagulation were higher than that in the scalpel group and endoscopic suture group (P<0.05);(2) The incidence of peri-menopausal syndrome in monopolar cautery group was higher than that in the ultrasonic scalpel group and en -doscopic suture group(P<0.05);(3) Serum decreased E2 and FSH increased postoperation in monopolar electro-coagulation group(P<0.05),which were statistically significant compared with other two groups (P<0.05).Con-clusion Monopolar coagulation can cause some damage on ovarian function .%目的：探讨腹腔镜卵巢囊肿剥除术中单极电凝止血对卵巢功能的影响。方法入院的150例单侧卵巢囊肿患者按照抽签方法随机地均分为三组，即超声刀组50例、镜下缝合组50例及单极电凝组50例。比较三组术前、术后2个月及术后4个月月经改变情况、围绝经期综合征发生情况及激素（ E2、FSH）水平。结果（1）单极电凝组患者术后月经改变例数均显著大于超声刀组与镜下缝合组（P＜0．05）；（2）单极电凝组患者围绝经期综合征发生率均显著大于超声刀组与镜下缝合组（P＜0．05）；（3）单极电凝组患者术后与术前相比，出现E2水平降低与FSH升高，差异有统计学意义（ P＜0．05），且与超声刀组及镜下缝合组患者的E2、FSH水平相比，差异均有统计学意义（P＜0．05）。结论单极电凝止血会对卵巢功能造成一定的损害。
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