Objective To investigate the association between urinary albumin creatinine ratio and Transcutaneous oxygen pressure in patients with type 2 diabetes mellitus. Methods Instep TcPO2 was detected by TCM400 Transcutaneous oxygen pressure in each patient of 360 type 2 diabetics. Urinary albumin creatinine ratio was measured by DCA2000 + albumin creatinine analyzer. Meanwhile, serum levels of triglyceride, total cholesterol, uric acid in overnight fasting blood speciments were tested. Results TcPO2 was negatively correlated with age, duration, smoke,hypertension, dyslipidemia, elevated blood uric acid, urine ACR, respectively, but not correlated with sex. Conclusion Abnormal TcPO2 may play a warning role not only in early diabetic microvasular dysfunction of lower limb, but also indicate diabetic renal damage.%目的 探讨2型糖尿病(T2DM)患者经皮氧分压(TcPO2)与尿白蛋白肌酐比(ACR)的相关性.方法 采用TCM400经皮氧分压检测仪检测360例T2DM患者足背TcPO2值;留取晨尿,采用DCA2000+白蛋白/肌酐分析仪检测尿ACR、留取过夜空腹血检测三酰甘油(TG)、总胆固醇(TC)和血尿酸水平.结果 TcPO2与年龄、病程、吸烟率、高血压、高血脂、血尿酸、尿ACR等因素呈负相关,与性别无相关性.结论 异常TcPO2不仅可反映下肢微血管功能状态,还能一定程度提示糖尿病肾脏损害.
展开▼
