Objective To observe effcicacy of polyp resection under hysteroscopic resection combined with applica -tion drospirenone ethinyl estradiol tablets (Yasmin) in treatment and prevention of endometrial polyp recurrence .Methods 106 patients with endometrial polyps were randomly divided into two groups , 53 cases in the observation group , received resec-tion of endometrial polyps and Yasmin oral treatment of three cycles;53 cases in the control group , only received resection of endometrial polyps .Follow-up of six months , the treatment effect and recurrence was observed and compared between the two groups.Results Significant improvement in the efficiency of the menstrual and the total effective rate were found in observa -tion group, which were better than the control group , the difference was statistically significant ( P <0.05) (73.6% vs. 45.3%, 94.3%vs.81.1%);Observation group's endometrial polyp recurrence rate was 7.5%, lower than the control group of 24.5%( P <0.05).Complications in the two groups did not occur , the observation group had mild nausea in 3 cases (5.7%), irritability, mood swings, irritability and other in 4 cases (7.5%), were spontaneous relieved.Conclusion Hyst-eroscopic endometrial polyp resection combined with Yasmin , which can effectively restore normal menstruation , reduce endo-metrial polyp recurrence rate , fewer adverse reactions , worthy of promotion .%目的：观察宫腔镜下子宫内膜息肉电切术后应用屈螺酮炔雌醇片（优思明）治疗和预防子宫内膜息肉复发的临床疗效。方法子宫内膜息肉患者106例，随机分为2组，观察组53例，行子宫内膜息肉电切术后口服优思明治疗3个周期；对照组53例，行子宫内膜息肉电切术后未用药物治疗。随访6个月，观察比较2组治疗效果及复发情况。结果观察组月经改善的显效率、总有效率均高于对照组（73唵．6％ vs．45．3％，94．3％ vs．81．1％），差异有统计学意义（ P ＜0．05）；观察组子宫内膜息肉复发率为7．5％低于照组的24．5％（ P ＜0．05）。2组均未发生并发症，观察组于服药初期出现轻微恶心3例（5．7％），烦躁、易怒等情绪波动4例（7．5％），均自行缓解。结论宫腔镜下子宫内膜息肉电切术后联合应用优思明，可有效恢复正常月经，降低子宫内膜息肉复发率，不良反应少，值得临床推广。
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