背景 眼前节解剖结构的生物学测量参数对于青光眼、眼外伤的诊治及人工晶状体(IOL)度数的测量具有重要意义.目的 比较Sirius与Pentacam测量前房深度及中央角膜厚度(CCT)的差异,并对两种仪器的测量结果进行一致性评价.方法 收集温州医学院眼视光学院在校学生38名,其中男20人,女18人；年龄23 ～ 32岁.每位受检者右眼分别用Pentacam和Sirius对前房深度和CCT进行测量,每种仪器对每眼测量3次,取平均值进行各种仪器的重复性和一致性评价,并对两种测量结果进行差异比较和一致性评价.结果 Pentacam测量的前房深度为(3.18±0.21) mm,组内相关系数(ICC)为0.995,变异系数(CV)为0.066；Sirius测量的前房深度为(3.22±0.21 )mm,ICC为0.996,CV为0.065.两种仪器测量前房深度的差值为0.04 mm,差异有统计学意义(t=-6.225,P＜0.05)；两种仪器测量前房深度的相关系数r=0.977；95％一致性区间为(-0.04 ～0.13)mm,位于均值的1个标准差区间±0.21 mm内,此结果临床上可以接受.Pentacam测量的CCT为(535±33) μm,ICC为0.994,CV为0.062；Sirius测量的CCT为(537±36) μm,ICC为0.999,CV为0.067.两种仪器测量的CCT相差2μm,差异无统计学意义(t=1.771,P＞0.05)；两种仪器测量CCT的相关系数r=0.985；95％一致性区间为(-11.64 ～15.65)μm,位于均值的1个标准差区间±34.27 μm内,此结果临床上可以接受.结论 Sirius与Pentacam测量前房深度及CCT的一致性较好,两种方法在对眼前节参数的测量时可相互替代,为临床眼前节参数的测量提供了一个新的选择.%Background Biometry of the anterior ocular segment parameter is very important for the diagnosis and treatment of glaucoma and ocular injury as well as measurement of intraocular lens(IOL). Objective This study was to compare the differences in the anterior chamber depth(ACD) and the central corneal thickness (CCT) between Sirius and Pentacam and evaluate the agreement of these two measurement methods. Methods The ACD and the CCT of 38 right eyes from 38 health volunteers aged 23- 32 years were measured with both Pentacam and Sirius.Three times of measurement were pedormed on each eye for each method to obtain the average values.The repeatability and agreement from each method were assessed as intraclass correlation coefficient( ICC ) and coefficient of variation(CV) and the agreement between these two methods were evaluated using Bland-Altman mode.Results The mean ACD value was( 3.18±0.21 ) mm from Pentacam with the ICC 0.995 and CV 0.066.The mean ACD value from Sirius was (3.22 ±0.21 )mm with the ICC 0.996 and CV 0.065.The difference value in ACD between two methods was 0.04 mm,showing a significant difference( t =-6.225,P＜0.05 ) and a positive correlation (r=0.977) between two methods.The 95％ limit of agreement was( -0.04-0.13)mm within 1 standard difference (SD) of the mean value( ±0.21mm),which was acceptable for clinical measurement.The CCT was( 535±33 )μm from Pentacam with the ICC 0.994 and CV 0.062.The CCT was(537±36)pm from Sirius with the ICC 0.999 and CV 0.067.The difference value in the CCT between two methods was about 2 μm,presenting a in significant difference ( t =1.771,P＞0.05 ) and positive correlation ( r =0.985 ).The 95 ％ limit of agreement was ( - 11.64-15.65 ) μm within 1 SD of the mean value( ±34.27 pm),which was acceptable for clinical measurement. Conclusions Sirius and Pentacam show good agreement in the measurement of ACD and CCT.The two methods offer an alternative choice for the biological measurement of the anterior ocular segment.
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