目的 了解胰腺癌患病情况并分析其危险因素.方法 将2010年9月至2016年9月本院收治的246例胰腺癌患者纳入病例组,选取同期于本院行健康体检的246例健康者纳入对照组,采用单因素和多因素Logistic回归分析探讨导致胰腺癌的危险因素.结果 单因素和多因素Logistic回归分析显示:吸烟(OR=2.318,95%CI:1.412~6.738)、酗酒(OR=1.673,95%CI:1.113~4.473)、糖尿病(OR=1.588,95%CI:1.107~4.687)、慢性胰腺炎(OR=1.433,95%CI:1.160~3.182)、胆石症(OR=1.071,95%CI:1.006~2.769)为胰腺癌患病的主要危险因素.结论 胰腺癌发病率呈逐年上升趋势,与吸烟、酗酒、慢性胰腺炎、糖尿病、胆石症等密切相关.%Objective To understand the prevalence and related risk factors of pancreatic cancer.Method 246 cases of pancreatic cancer patients in our hospital from September 2010 to September 2016 were enrolled in case group, 246 healthy persons during the same period were enrolled in control group. Single and multivariable factors Logistic regression analysis were used to analyze the risk factors.Result The prevalence rate of pancreatic cancer was higher, a rising trend year by year, men more than women. After single and multiple factors Logistic regression analysis, smoking (OR=2.318, 95%CI: 1.412~6.738), alcohol (OR=1.673, 95%CI: 1.113~4.473), diabetes (OR=1.588, 95%CI: 1.107~4.687), chronic pancreatitis (OR=1.433, 95%CI: 1.160~3.182) and cholelith dise ase (OR=1.071, 95%CI: 1.006~2.769) were the major risk factors of pancreatic cancer.Conclusion The incidence of pancreatic cancer is increasing year by year, which is closely related to smok ing, alcoholism, chronic pancreatitis, diabetes, cholelithiasis and so on.
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