Th17细胞是近年来新发现的一类CD4+T细胞亚群,主要通过分泌白细胞介素17等细胞因子发挥促炎作用,参与多种自身免疫性疾病的发病过程.本文就Th17细胞及其相关细胞因子与肾脏病的关系进行综述,以期更深入地认识肾脏病的发病机制,为肾脏病诊治寻找新的靶点提供依据.%T helper 17 cells ( Th17) are a subset of T helper cells producing interleukin 17 (IL-17). They are considered developnientally distinct from Thl and Th2 cells and excessive amounts of the cell are thought to play a key role in autoimmune disease. Accumulating evidence suggests that Th17 cells and cytokines participate in human and experimental renal disease. This article reviews the progress on the role of Th17 cells and cytokines in the pathogenesis of kidney diseases.
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