以四氢吡喃-4-酮与芳香醛(1)为原料,NH2SO3H为催化剂,在无溶剂条件下,微波促进Aldol缩合反应合成了一系列3,5-二亚苄基四氢吡喃4-酮衍生物(收率72％～92％),其结构经1H NMR,IR,MS和元素分析确证.最佳反应条件为:1 12 mmol,NH2SO3H用量40 mol％,于300 W微波辐射2 min～3 min.%A series of 3,5-dibenzylidene-tetrahydropyran-4-one derivatives with yield of 72％ ～ 92％ were synthesized by Aldol condensation of tetrahydro-4H-pyran-4-one with aromatic aldehydes(1) using NH2SO3H as the catalyst under solvent-free condition and microwave irradiation.The structures were confirmed by 1H NMR,IR,MS and elemental analysis.The optimum reaction conditions were as follows:1 was 12 mmol,NH2SO3H amount was 40 mol％,microwave irradiation at 300 W for 2 min ～ 3 min.
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