目的 探讨超声造影、超声弹性成像技术对甲状腺良恶性结节的鉴别诊断价值.方法 对189个甲状腺结节患者行弹性成像及超声造影检查,均经手术或穿刺活检病理证实,评估各诊断方法的敏感性、特异性、阳性预测值、阴性预测值和准确率,并用ROC曲线下面积评价各方法的诊断价值.结果 超声造影、弹性成像对于甲状腺结节的定性诊断均有较高的价值,敏感性、特异性、准确率分别为88.24％、90.34％、89.67％及85.29％、88.97％、87.89％,而超声造影联合弹性成像诊断效率最高,敏感性为98.53％,特异性为96.55％,准确率为97.18％,且差异具有统计学意义.结论 超声造影和超声弹性成像对甲状腺良恶性结节具有较高的诊断价值,是较有前途的超声检查技术,综合考虑更有助于提高诊断的信心.%Objective To evaluate the value of contrast-enhanced ultrasound(CEUS) and ultrasonic elastography (UE) in diagnosis of thyroid nodules.Methods 189 cases of thyroid nodules confirmed by pathology were underwent CEUS and UE.The sensitivity,specificity,positive predictive,negative predictive and diagnostic rate of CEUS and UE were evaluated.Receiver operating characteristic(ROC) curve was constructed to assess the differential diagnosis value of CEUS and UE.Results The sensitivity,specificity,and diagnostic rate of CEUS and UE were 88.24 ％,90.34 ％,89.67％ and 85.29％,88.97％,87.89％,retrospectively.The sensitivity,specificity and diagnostic rate of UE combined with CEUS were 98.53％,96.55 ％ and 97.18％,the difference had statistical significance compared with CEUS and UE.Conclusions Both CEUS and UE have high value in differential diagnosis of thyroid nodules,the combined of two methods can improve diagnostic rate.
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