PubMed is a database used to retrieval biomedical literatures. It, however, can't help us find out the hot topics in recent years. Nowadays, there are some researchers working on the comparative analysis about different tools as same as PubMed, and some other ones bend themselves to data mining on one special field. Our research is finding out the hot topics by analyzing the numbers of publications of some keywords. Here we referred to Time Magazine to list 34 keywords, used E-utilities to get the numbers of publications from PubMed automatically. By analyzing these numbers we can then conclude the hot topics in recent years.%PubMed是检索生物医学方面文献的数据库之一,但是它不能从众多文献中找出近年来的热点话题.现在,一些研究人员在从事分析比较不同检索工具的优缺点的工作,一些主要从事某一特定领域的数据挖掘工作.本文从《时代周刊》中找到34个生物医学领域的关键词,用PubMed提供的E-utilities编程接口编写程序并自动从该数据库中获得涉及关键词的文献数目,最后通过分析数据得到最近十年里生物医学方面的十大热点话题.
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