In this experiment,5-halogenated salicylaldehyde thiosemicarbazone (Ⅰ) was prepared by the condensation reaction between 5-halogenated salicylaldehyde and thiosemicarbazide.Then,the reflux reaction between 5-halogenated salicylaldehyde thiosemicarbazone (Ⅰ) and 2-bromo-1-phenylethanone or 2-bromo-1-(4-methoxyphenyl) ethanone was carried out for 10 min to gain 5-halogenated-2-(4-aryl-thiazole-2-radical)-phenol-methyl hydrazone.All products were characterized by IR,NMR,and mass spectrometry.%以5-卤代-水杨醛为原料,与氨基硫脲发生缩合反应,生成5-卤代-水杨醛缩氨基硫脲.然后分别与ω-溴代苯乙酮、对甲氧基-ω-溴代苯乙酮在甲醇或丙酮溶剂中回流反应10 min,得到6个5-卤代-2-(4-芳基-噻唑-2-基)-腙甲基-苯酚,最后通过红外、核磁、质谱对其进行了结构表征.
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