目的分析并探讨肾黏液管状梭形细胞癌的临床特征。方法对1例左肾黏液管状梭形细胞癌病例的临床资料进行回顾性分析,其由于出现不明原因发热等症状住院就诊,进行根治性肾癌切除术,肿瘤大小约100mm×70mm,临床分期为T2N0M0,其病理表现为排列成簇的狭长小管状上皮细胞,中间充满黏液间质和梭形细胞,免疫标记示Vimentin(++)、p504S(++)、CD10(-)、CK7(-)、Villin(-)、E-cad(-)。结果术后1d体温基本恢复正常,术后1年随访出现胸12椎体转移,第3年死亡。结论肾黏液管状梭形细胞癌属于低度恶性肾上皮性肿瘤,免疫组化分析其可能来源于远端肾小管,可出现神经内分泌分化,早期采用手术切除可取得较好的预后。% Objective To analyze and discuss the clinical features of renal tubular mucus spindle cell carcinoma. Methods 1 patients with left renal mucus tubular spindle cell carcinoma of the clinical data were retrospectively analyzed, The patientcame to the hospital with fever of undetermined origin.The size of thetumorwas 100mm×70mm.Clinical stage:T2N0M0.Histologic feature:tumors consisted of tightly packed,small,elongated tubules separated by pale mucinousstrom.The tumor cells were cuboidal to spindled with eosinophiliccytoplasm.The Immunohistochemical staining of the tumor is Vimentin(++)、p504S(++)、CD10(-)、CK7(-)、Villin(-)、E-cad(-). Results After one day temperature basic back to normal, after one year follow-up appear bosom 12 vertebral transfer, the third year death. Conclusion The kidney mucous tubular spindle cells is a kind of cancer low-grade malignant renal epithelial neoplasm, immunohistochemistry analysis may originate from the distal renal tubular, can appear neuroendocrine differentiation, early surgery treatment can acquire better prognosis.
展开▼
