OBJECTIVE:To probe into clinical pharmacists ' drug selection , monitoring on adverse drug reactions and countermeasures for patients with endocarditis infected by methicillin-resistant staphylococcus aureus ( MRSA) in particular cases . METHODS: To retrospectively analyze the data of 1 case of MRSA infectious endocarditis . RESULTS: The patient was given levofloxacin hydrochloride for injection , vancomycin hydrochloride , caspofungin acetate for injection and daptomycin injection one after another for anti-infective therapy .During treatment , the patient suffered tardive red man syndrome and secondary fungal infection .Clinical pharmacists had analyzed the causes and given clinicians assistance for adjusting therapeutic regimen , the patient went better after and was approved to discharge from hospital .CONCLUSIONS: Clinical pharmacists give full play of professional advantages to assist clinicians in formulating or adjust therapeutic regimen aiming at patients in severe condition and with adverse drug reactions, so as to ensure safe and effective medication .%目的:探讨临床药师对耐甲氧西林金黄色葡萄球菌(methicillin-resistant staphylococcus aureus,MRSA)感染的心内膜炎患者特殊情况下的药物选择、不良反应监测及处理.方法:回顾性分析1例MRSA感染性心内膜炎病例资料.结果:先后给予该患者注射用盐酸左氧氟沙星、盐酸万古霉素、注射用醋酸卡泊芬净和注射用达托霉素抗感染治疗,治疗过程中出现迟发性红人综合征,继发性真菌感染.临床药师分析相关原因并协助医师调整用药方案,患者病情持续好转,准予出院.结论:临床药师发挥专业优势,针对重症、发生不良反应的患者,协助医师制订或调整用药方案,可保障用药安全有效.
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