Objective:To probe into the anesthetic effects of sevoflurane for lower abdominal and perineum surgery in children.METHODS: 90 children <7 years old undergoing lower abdominal and perineum surgery admitted into the Third People`s Hospital of Zhaoqing from Jan.2015 to Jan.2017 were selected to be divided into observation group and control group via the random number table,with 45 cases in each.The control group was given traditional ketamine anesthesia,while the observation group received sevoflurane.Changes of MAP,HR,postoperative awake time,agitation and adverse drug reactions in two groups were observed and compared.RESULTS: MAP and HR in observation group at different time points were significantly lower than that of control group,with statistically significant difference(P<0.05).The postoperative awake time of observation group was(6.2±3.8)min,significantly shorter than that of control group [(19.5±3.6)min].Meanwhile,incidences of agitation and adverse drug reactions in observation group were respectively 6.67％(3/45),2.22％(1/45),significantly lower than those in control group[22.22％(10/45),6.67％(3/45)],with statistically significant difference(P<0.05).CONCLUSIONS: Compared with traditional ketamine anesthesia,sevoflurane for lower abdominal and perineum surgery in children has fewer adverse drug reactions and higher safety.%目的:探讨七氟醚用于儿童下腹部与会阴部手术的麻醉效果.方法:选取2015年1月-2017年1月肇庆市高要区人民医院收治的<7岁腹部和会阴部手术患儿90例,采用随机数字表法分为对照组与观察组,每组45例.对照组患儿采用传统氯胺酮麻醉,观察组患儿采用七氟醚麻醉.对比观察两组患儿不同时间点的平均动脉压(MAP)、心率(HR)变化情况,术后清醒时间、躁动情况及不良反应.结果:观察组患儿各时间点的MAP、HR均明显低于对照组,差异均有统计学意义(P<0.05).观察组患儿术后清醒时间为(6.2±3.8)min,明显短于对照组的(19.5±3.6)min;观察组患儿躁动发生率、不良反应发生率分别为6.67％(3/45)、2.22％(1/45),明显低于对照组的22.22％(10/45)、6.67％(3/45),差异均有统计学意义(P<0.05).结论:七氟醚适用于儿童下腹部及会阴部手术麻醉,与传统氯胺酮麻醉比较,其不良反应更少,安全性更高.
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