OBJECTIVE:To probe into the clinical efficacy of fluticasone propionate combined with terbutaline in treatment of chronic obstructive pulmonary disease (COPD) with acute exacerbation.METHODS:90 cases with COPD with acute exacerbation admitted into Yingkou Zhanqian District Control Station from Feb .2015 to Mar.2016 were selected to be divided into observation group and conventional group via the random number table , with 45 cases in each.The conventional group were treated with terbutaline , while the observatio group were additionally given terbutaline inhalation based on the conventional group .The clinical efficacy and blood indicators of two groups were compared between two groups .RESULTS:The total effective rate of observation group was 97.78%(44/45), significantly higher than that of conventional treatment 75.56%(34/45), with statistically significant difference(P0.05), the arterial partial pressure of oxygen , partial pressure of carbon dioxide of observation group were significantly better than those of conventional treatment , with statistical significance (P<0.05). CONCLUSIONS: The efficacy of fluticasone propionate combined with terbutaline in treatment of COPD with acute exacerbation is remarkable , which can effectively improve patients ’ clinical symptoms .%目的：探讨丙酸氟替卡松联合特布他林治疗慢性阻塞性肺疾病急性加重期的临床疗效。方法：选取2015年2月—2016年3月营口市站前区防治总站收治的慢性阻塞性肺疾病急性加重期患者90例作为研究对象。按照随机数字表法分为观察组和对照组，每组各45例。对照组患者给予特布他林，观察组患者在对照组基础上给予丙酸氟替卡松气雾剂。比较2组患者的临床疗效及治疗前后的血气指标变化情况。结果：观察组患者的总有效率为97．78％（44／45），显著高于对照组的75．56％（34／45），差异有统计学意义（P＜0．05）；治疗后，2组患者pH的差异无统计学意义（P＞0．05），观察组患者的动脉血氧分压、二氧化碳分压均显著优于对照组，差异有统计学意义（ P＜0．05）。结论：丙酸氟替卡松联合特布他林治疗慢性阻塞性肺疾病急性加重期的疗效显著，能有效改善患者临床症状。
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