OBJECTIVE:To investigate the utilization of pantoprazole sodium for injection in prevention of stress ulcer in Traditional Chinese Medicine Hospital of Kaifeng City ( hereinafter referred to as “our hospital”) , and to evaluate the rationality of drug use .METHODS:512 medical records with the utilization of pantoprazole sodium for injection in prevention of stress ulcer from our hospital in 2014 were randomly selected to conduct the analysis and evaluation in terms of medicinal indication , the usage of solvents , route of administration , dosage and frequency of administration and course of treatment etc .RESULTS:The proportion of medical records with pantoprazole sodium for injection without indications were the highest , reached 63.48%( 325/512 ) .The usage of solvent and route of administration were basically rational;the frequency of the single dose was under rationality; the treatment course of medical records for 1,2,3-7,7-14 d accounting for 11.33%(58/512),9.57%(49/512), 51.98%(261/512) and 28.13%(144/512), respectively.CONCLUSIONS: The rationality of utilization of pantoprazole sodium for injection in prevention of stress ulcer need to be further strengthened in our hospital .%目的：了解开封市中医院（以下简称“我院”）注射用泮托拉唑钠预防应激性溃疡的使用情况，评价用药合理性。方法：随机抽查我院2014年预防应激性溃疡使用注射用泮托拉唑钠的病历512份，对其用药指征、溶剂使用情况、给药途径、用药剂量及频率、用药疗程等进行分析、评价。结果：无指征使用注射用泮托拉唑钠的病历所占比例最高，达63.48％（325／512）；溶剂使用情况和给药途径基本合理；单次给药剂量的频率欠合理；给药疗程为1、2、3～7、7～14 d的病历分别占11.33％（58／512）、9.57％（49／512）、51.98％（261／512）、28.13％（144／512）。结论：我院注射用泮托拉唑钠预防应激性溃疡的用药合理性有待加强。
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