OBJECTIVE: To investigate the characteristics and regularity of the adverse drug reactions ( ADRs) occurred in Shaanxi Yulin First Municipal Hospital ( hereinafter referred to as “our hospital”) so as to reduce the incidence of ADR and promote rational use of drugs. METHODS:A total of 381 ADR case reports collected by clinical pharmacy room of pharmacy department of our hospital in 2013 were statistically analyzed and evaluated using regression analysis. RESULTS:Of the 381 ADR cases, males showed high proportion than females [(52�76%(201 cases) vs. 47�24%( 180 cases ) ]; the patients aged 51⁃70 years took the lead with 240 cases ( 62�99%); the inpatients outnumbered the outpatients [ 348 ( 91�34%) vs. 33 ( 8�66%) ];173 cases ( 45�41%) were induced by anti⁃infective drugs,327 cases(85�83%) by intravenous drip infusion;156 cases(40�94%) manifested as lesions of skin and its appendages. 342(89�76%) were common ADRs;303(79�53%) were cured;171 cases(44�88%) were considered as “most probably” in cause⁃effect relationship. CONCLUSIONS: The occurrence of ADR is closely associated with clinic;it is important for hospital to attach great importance to the ADR monitoring and reporting so as to promote clinical rational use of drugs.%目的：了解陕西榆林市第一医院（以下简称“我院”）药品不良反应（ ADR）发生的特点和规律，以期减少ADR的发生，促进合理用药。方法：采用回归性分析法对2013年我院药剂科临床药学室收集的381份ADR报告进行统计分析、评价。结果：381例ADR报告中，发生ADR的男性患者（201例，占52�76％）多于女性患者（180例，占47�24％）；51～70岁的中老年患者（240例，占62�99％）多于其他年龄段患者；住院患者（348例，占91�34％）多于门诊患者（33例，占8�66％）；引发ADR的药物以抗感染药为主（173例，占45�41％）；给药途径以静脉滴注为主（327例，占85�83％）；ADR 的主要临床表现为皮肤及其附件损害（156例，占40�94％）；ADR报告类型多为一般的ADR（342例，占89�76％），结果多表现为痊愈（303例，占79�53％），发生的因果关系多为“很可能”（171例，占44�88％）。结论：ADR的发生与临床密切相关，医院应予以重视，加强对ADR的监测和上报工作，促进临床合理用药。
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