Coenzyme Q10 soft capsule were consecutively orally given to mice with the doses of 33.5, 67, 134 mg/kg·bw (5,10,20 times to the recommended human dosage) for 30 d. The spleen lymphocyte transformation efficiency, delayed type hypersensitivity, antibody-producing, Monocyte-macrophage carbon clearance ability, Peritoneal macrophage phagocytic capacity and the activity of natural killer ( NK )were determined. The results showed that Coenzyme Q10 soft capsule can promote the proliferation of mouse spleen lymphocytes and transformation of mice'S spleen lymphocytes and the proliferation of antibody-producing cells in mice, increased levels of serum hemolysin in mice, promote delayed hypersensitivity and its monocyte-macrophage phagocytosis. Therefore, Coenzyme Q10 soft capsule can be determined in mice with enhanced immunity.%分别以33.5、67.0、134.0 mg/kg·BW（相当于人体推荐用量5、10、20倍）剂量的辅酶Q10软胶囊给小鼠连续灌胃30 d，分别测定ConA诱导的小鼠淋巴细胞转化功能、小鼠的迟发型变态反应、小鼠抗体生成和溶血素水平、单核-巨噬细胞碳廓清能力、腹腔巨噬细胞吞噬鸡红细胞能力以及NK细胞活性。结果显示辅酶Q10软胶囊能促进小鼠的脾淋巴细胞增殖、转化作用，促进小鼠的抗体生成细胞增殖，提高小鼠的血清溶血素水平，促进小鼠的迟发型变态反应及其单核-巨噬细胞的吞噬功能，因此，可判定辅酶Q10软胶囊具有增强小鼠免疫力的作用。
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