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慢性萎缩性胃炎的中医体质特点与病理改变的相关性研究

         

摘要

目的:探讨慢性萎缩性胃炎的中医体质特点及与病理改变的相关性。方法采用《中医体质分类与判定标准》表,调查141慢性萎缩性胃炎患者的中医体质分布特点,并观察胃镜下胃黏膜的萎缩程度、不典型增生程度、肠化程度及HP感染情况后做统计学分析。结果141例慢性萎缩性胃炎中虚性体质(51.1%)高于实性体质(39.7%)和平和体质(9.2%),三组差异性显著(P<0.01)。胃黏膜的萎缩程度及肠化程度与阴虚体质和瘀血体质有相关性( P<0.05)。不典型增生和幽门螺杆菌感染似无相关性( P>0.05)。结论慢性萎缩性胃炎以虚性体质居多。胃黏膜的病理改变与中医体质有一定相关性。%Objective To survey the TCM constitutional characteristics in the patients with chronic atrophic gastric(CAG),and state the relationships between constitutions characteristics and histopathological changes.Methods The constitutional types of 141 CAG patients were investigated by applying the standard in Classification and Determination of TCM constitutions.Information collection included the TCM constitution types, the examination of Hp infection, the gastro cope check results .The correlation between TMC constitutional characteristics and histopathlogical manifestations were analyzed by using statistical methods.Results Among 141 CAG cases, deficiency constitution was accounted for 51.1%,excessive constitution accounted for 39.7%and the moderate was 9.2%.The difference of these three were statically significant ( P<0.01). If the CAG patient were Yin Xu zhi and Yu Xue zhi ,their shrink level of gastric mucosa was usually serious and intestinal metaplasia (IM) was common (P <0.05).However, the atypia (ATP) and Hp infection were not related with the TCM constitution types (P>0.05).Conclusion The TCM constitution of CAG was mostly deficiency.There is relationship between the TCM constitution and histopathological changes.

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