Objective To know anxiety and depression emotions of early pregnant women with adverse drug reactions and their inlfuencing factors, and to explore inlfuence of nursing intervention on anxiety and depression emotions. Method 148 cases of early terminated pregnant patients with adverse drug reactions were measured with self-rating anxiety scale (SAS), self-rating depression scale (SDS) and social support rating scale (SSRS). According to ages, they were divided into low-age group(≤30) and advanced-age group(>30). There were 74 cases in each group. General nursing intervention was applied to these cases. For patients of two groups, anxiety and depression emotions before and after drugs were taken as well as incidence of adverse drug reaction after drugs were taken were assessed and compared. Result Standard scores of anxiety and depression emotions prior to nursing intervention were higher than national norms. The comparison difference was statistically signiifcant(P<0.01). There was signiifcant negative correlation between standard scores of anxiety and depression emotions and subjective support score, social support score and utilization of support respectively(P<0.01). There was no correlation between standard scores of anxiety and depression and objective support(P>0.01). There were statistically signiifcant differences between two groups in social support score, subjective support and objective support(P<0.01). There was no statistical signiifcance between two groups in utilization of support(P>0.01). For low-age group, comparison differences between anxiety and depression emotions before and after nursing intervention were statistically signiifcant(P<0.05). For advanced-age group, comparison differences between anxiety emotions before and after nursing intervention were no statistical signiifcance(P>0.05). For advanced-age group, comparison differences between depression emotions before and after nursing intervention were statistically signiifcant(P<0.05). Conclusion It’s normal for early pregnant women with adverse drug reactions to appear anxiety and depression emotions. General nursing intervention can help to improve anxiety and depression emotions. Advanced-age group should be paid close attention.%目的：了解出现药物不良反应人工流产妇女流产前的焦虑抑郁状况及其影响因素，探索综合护理干预对焦虑抑郁情绪的影响。方法采用焦虑自评量表（SAS）、抑郁自评量表（SDS）、社会支持评定量表（SSRS），对将出现药物不良反应的148例早孕终止妊娠妇女进行测评，同时按年龄分为低龄组（≤30岁）和高龄组（＞30岁）两组，每组各74例，给予综合护理干预并观察两组用药前后焦虑抑郁情绪和用药后药物不良反应的发生情况，并进行测评比较。结果护理干预前的焦虑抑郁标准分均高于国内常模，比较差异有统计学意义（P＜0.01）、焦虑、抑郁标准分与主观支持分、社会支持总分、支持利用度呈显著负相关（P＜0.01）；焦虑、抑郁标准分与客观支持零相关（P＞0.01），低龄组与高龄组的社会支持总分、主观支持、客观支持比较差异有统计学意义（P＜0.01）；低龄组与高龄组的支持利用度比较，差异无统计学意义（均P＞0.01）；低龄组护理干预前后焦虑、抑郁比较，差异均有统计学意义（P＜0.05），高龄组护理干预前后焦虑比较，差异无统计学意义（P＞0.05），高龄组护理干预前后抑郁比较，差异有统计学意义（P＜0.05）。结论出现药物不良反应人工流产妇女的焦虑抑郁情绪常见，综合性护理干预能改善焦虑抑郁情绪，应重点关注高龄组群体。
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