Objective To study the epidemiological features of chlamydia pneumoniae infection in children with respiratory disease. Methods Serum specific IgM was detected in 1027 children of respiratory disease in our hospital from January 2009 to December 2011 by enzyme-linked immunosorbent assay (ELISA), and the characteristics of Chlamydia pneumoniae infection in children and popular distribution were analyzed. Results ①The positive rate of serum Chlamydia pneumoniae IgM was 35.2% from 2009 to 2011, which was the highest in 2010 (42.6%) and the lowest in 2009 (29.2%). ② Children of 0 to 6 months old had the lowest positive rate (12.0%), significantly lower than the overall level (P<0.01). Children of 10 to 12 years old had the highest positive rate (45.9%), and those of 7 to 9 years old or10 to 12 years old had a positive rate significantly higher than the overall level (P<0.05). ③The positive rate was found to be the highest in December (44.7%) and the lowest in July 25.6%, P<0.01. Conclusion Children with respiratory disease have high prevalence and incidence of chlamydia pneumoniae infection, mainly in spring and winter. Chlamydia pneumoniae infection might be related to immunity in children and cross-infection.%目的 研究肺炎衣原体在儿童中的流行特点,为临床诊治提供依据.方法 选择2009 年1 月至2011 年12 月间在我院门诊就诊的呼吸道感染患儿1 027 例,采用酶联免疫吸附法(ELISA)检测患儿血清特异性IgM,分析儿童肺炎衣原体感染情况及流行分布特点.结果 ①患儿血清肺炎衣原体IgM 阳性率为35.2%.2010 年阳性率最高,为42.6%,2009 年阳性率最低,为29.2%.② 0~6 个月患儿肺炎衣原体IgM 阳性率最低,为12.0%,明显低于总体水平(P<0.01);10~12 岁IgM阳性率最高,为45.9%,7~9 岁、10~12 岁IgM阳性率明显高于总体水平(P<0.05).③12 月份受检患儿肺炎衣原体IgM 阳性率最高,为44.7%;8 月份受检患儿阳性率最低,为25.6%,两者比较差异有统计学意义(P<0.01).结论 呼吸道疾病患儿肺炎衣原体感染率较高,春季和冬季是高发月份,衣原体感染可能与患儿机体免疫力及交叉感染有关.
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