目的：探讨腹腔镜下完整结肠系膜切除（ complete mesocolic excision ，CME）在结肠癌手术治疗中的应用效果。方法回顾性分析接受手术治疗的结肠癌患者的临床资料，其中CME手术治疗组（ CME 组）45例，传统结肠癌根治术治疗组（对照组）37例，观察对比两组的肿瘤根治性指标、手术及术后相关指标和预后情况。结果 CME组的总清扫淋巴结数、Ⅲ期清扫淋巴结数及Ⅲ期淋巴结阳性数均显著高于对照组（均P＜0．05）；两组术后30 d及术后1年的复发率、死亡率比较，差异无统计学意义（P ＞0．05）；CME组术后2年的复发率、死亡率均显著低于对照组（P＜0．05）。 CME 组术中出血量明显少于对照组（P＜0．05）。两组的手术时间、住院时间、术后排气时间及排便时间比较，差异均无统计学意义（P＞0．05）。结论 CME可以实现结肠癌的根治性完整切除，提高根治效果和患者近期预后。%Objective To evaluate the efficacy of laparoscopic complete mesocolic excision ( CME) in treating colon cancer . Method The clinical data of patients with colon cancer were retrospectively analyzed .They were divided into the CME group (45 cases as the experimental group ) and the control group (n=37) treated with traditional colon cancer surgery . The radical tumor targets , surgery and related indexes and prognosis of the two groups were compared .Findings The total number of lymph node dissection , the number of lymph nodes and Ⅲ number of positive lymph nodes of the CME group were significantly higher than those of the control group ( P <0 .05 ) .No statistically significant difference was found between the two groups in mortality rate and recurrence rate 30d and 1-year after operation (P>0.05);2-year recurrence rate and mortality rate of the CME group were significantly lower than those of the control group (P<0.05).Blood loss of the CME group was significantly less than that of the control group (P<0.05).Surgery time, hospital stay, postoperative exhaust time and defecation time of the two groups showed no statistically significant difference (P>0.05).Conclusion CME can successfully produce complete radical resection of colon cancer and enhance the effect of short -term prognosis .
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