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二维斑点追踪技术定量评价心脏手术患者的右心室功能

     

摘要

Objective To understand the value of two-dimensional speckle tracking ( 2D-STI ) as a technology for determining the right ventricular function of patients having undergone cardiac surgery.Method 46 cases of cardiac surgery were first divided into two groups, one having abnormal LVEF ( LVEF <50%) and the other having normal LVEF (LVEF≥50%).They were then divided into an off-pump group (OP group) (n=21) and a CPB (CPB group) (n=25) according to the surgical method employed.30 healthy patients were also chosen to form the control group for study. Less than one week before surgery, all groups were subjected to color Doppler ultrasonographic test.QLAB 6.0 TMQA software was utilized for speckle tracking at the right ventricular endocardial contours and to compute the time curves and velocity of the right ventricular segmental strain, the right ventricular free wall three segments ( basal, middle segment and apical segments) so as to obtain the longitudinal peak systolic strain (ε) and peak velocity ( S) as the standard values for evaluating the right ventricular function.One week after the tests, a one month follow-up was conducted.Findings The longitudinal peak systolic and peak velocities of the right ventricular free wall three segments observed in the LVEF abnormal group significantly decreased (P<0.05), while the control group with normal LVEF between the two groups had no significant difference (P>0.05) .One week later, longitudinal peak systolic peak velocity of the right ventricular free wall three segments observed in the OP group as compared with that of the CPB group was significantly lower than before surgery (P <0.05).One month after surgery, recovery could be recognized.However, there were no significant differences (P>0.05).Conclusion (2D-STI) can serve as an efficient technology for determining ventricular function of patients after cardiac surgery.It can help to make well informed judgment of the severity of illness, prognosis, and surgical strategy.%目的:探讨二维斑点追踪技术(2D-STI)对心脏手术患者右心室功能的诊断价值。方法将46例心脏手术患者分为左心室射血分数( LVEF)异常组( LVEF<50%)和LVEF正常组( LVEF≥50%),根据手术方法进一步分为非体外循环组( OP组,21例)和体外循环组( CPB组,25例),另选取健康对照组30例,在术前1周内行超声心动图检查,采用QLAB 6.0 TMQA软件对右心室心内膜轮廓进行斑点追踪,并自动计算出右心室游离壁基底段、中间段及心尖段收缩期纵向峰值应变(ε)及峰值运动速度( S)作为右心室功能的评价指标,术后1周、1个月进行随访评价。结果术前LVEF异常组右心室功能右心室游离壁3个节段纵向收缩期峰值及峰值速度均较LVEF正常组明显下降,差异有统计学意义(P<0.05),而LVEF正常组与对照组组比较差异无统计学意义(P>0.05)。术后1周时,OP组与CPB组右心室游离壁3个节段纵向收缩期峰值及峰值速度均较术前明显降低,差异有统计学意义( P<0.05),术后1个月时均有明显恢复,与术前及对照组比较,差异无统计学意义(P>0.05)。结论二维斑点追踪技术可作为评价心脏手术患者术后右心室功能的有效方法,对危重患者的识别、预后判断及防治策略具有重要意义。

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