AIM: To study the efficacy of a single intravitreal injection of perfluoropropane ( C3F8 ) in releasing vitreomacular traction.METHODS: Twelve eyes of 12 consecutive patients with vitreomacular traction received a single intravitreal injection of 0. 3mL 100% ( C3 F8) were retrospectively analyzed. The best corrected vision acuity and the neural epithelium thickness of central macular were observed.RESULTS: One month following treatment, vitreomacular traction was released in 5 eyes (42%), mean final visual acuity (VA) improved 0. 04 and mean central foveal thickness decreased by 69μm. The vision acuity before and after treatment were 0. 20 ±0. 07, 0. 25 ± 0. 04 respectively.CONCLUSION: Intravitreal C3 F8 injection could offer a minimally invasive alternative to pars plana vitrectomy in patients with vitreomacular traction.%目的:观察研究玻璃体腔注射膨胀气体全氟丙烷(C3F8)治疗玻璃体黄斑牵引综合征的疗效.方法:回顾分析12例12眼玻璃体黄斑牵引综合征患者玻璃体腔注射0.3mL C3F8后1mo玻璃体黄斑牵拉情况以及最佳矫正视力、黄斑中心神经上皮厚度的变化情况.结果:玻璃体黄斑牵拉状态完全解除5眼(42%).治疗前后患者平均视力分别为0.20 ±0.07,0.25±0.04.黄斑中心神经上皮最大厚度平均减少69μm.结论:玻璃体腔注射C3F8是一种治疗玻璃体黄斑牵引综合征的有效方法,并且与玻璃体切除手术相比较创伤更小、安全性更高.
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