目的：探讨卒中后抑郁（ PSD）患者交感神经皮肤反应（ SSR）的特点及临床意义。方法共采集脑卒中患者88例，根据汉密尔顿抑郁量表（ HAMD）、抑郁自评量表（ SDS）评分将脑卒中患者分为无抑郁组、轻中度抑郁组、重度抑郁组，选取22名健康人群作为健康对照组。各组患者分别进行SSR测定，记录首次达峰时间及SSR波幅并进行比较分析。结果本组脑卒中患者PSD发生率为67．05％，PSD组与健康对照组相比，SSR首次达峰时间延长；波幅减低（均P＜0.05）。 PSD组与无抑郁组相比，SSR首次达峰时间延长；SSR波幅减低（ P＜0.05）。重度抑郁组与轻中度抑郁组相比， SSR 首次达峰时间延长；SSR 波幅减低（均P＜0.05）。结论 PSD患者SSR明显异常，抑郁越重，其异常程度越明显，SSR检测可有助于PSD诊断。%Objective To explore the characteristic of sympathetic skin response ( SSR) in patients with post-stroke depression ( PSD) and the clinical significance .Methods Eighty-eight patients with stroke were evaluated by the Hamilton Depression Scale ( HAMD ) and the Self-Rating Depression Scale ( SDS ) , and divided into no depression group , mild to moderate depression group and severe depression group , 22 healthy people were introduced into control group .Their SSR was determined , and the first peaktime and amplitude of SSR .The results were compared and analyzed.Results The incidence of PSD was 67.05%in 88 stroke patients.The study group revealed prolonged first peak time and lower amplitude of SSR compared to control group and no depression group ( all P<0.05).The severe depression group exhibited a longer first peak time and a lower amplitude of SSR than mild to moderate depression group ( all P<0.05 ) .Conclusions SSR in patients with PSD are abvious abnormality , the more serous the degree of depression in patients with PSD is , the more obvious the degree of abnormal .SSR may be helpful in diagnosis of PSD is .
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