Objective To investigate the relationship between early ST-segment resolution magnitude and short term prog-nosis after successful primary PCI in ST-elevated AMI ( STEMI) patients.Methods 140 consecutive STEMI patients who underwent primary PCI were enrolled in this study.ST-segment resolution was calculated and the patients were divided in-to group A (n=84,ΣSTE resolved≥50%) and group B (n=56,ΣSTE resolved <50%).TIMI flow after PCI, clinical events 1~3 weeks after PCI and cardiac function about 7 days after PCI were assessed.Multifactor regression analysis was used to identify the factors that may affect major adverse cardiovascular events ( MACE) in the in-hospital period.Results LVEF was higher in group A than that of group B, (54.1 ±5.1)%vs.( 46.7 ±4.0)%, P<0.05.The incidence of in-hospital MACE was also significantly less in group A than that in group B (6.0%vs.25.0%, P<0.05).Multivariate re-gression analysis showed that ΣSTR、symptom-onset -to-coronary revisualization time and diabetes were independent predictors in hospital adverse outcomes.Conclusion Early ST-segment resolution after primary PCI is the strongest inde-pendent predictor in in-hospital adverse outcomes for STEMI patients.%目的：分析ST段抬高型急性心肌梗死（ STEMI）直接经皮冠状动脉介入治疗（ PCI）后心电图ST段早期回落和近期预后的相关性。方法 STEMI患者140例，按PCI后2 h心电图相关导联ST段抬高总和较术前的下降百分比（ΣSTR）分为A组（ΣSTR≥50％，84例）和B组（ΣSTR＜50％，56例），比较两组患者PCI后梗死相关动脉（ IRA）的TIMI血流分级、术后1周左心室射血分数（ LVEF）及住院期间严重心脏不良事件（ MACE）发生情况，对可能影响住院期间MACE的因素进行Logistic多因素回归分析。结果 A组术后1周LVEF（54．1±5．1）％明显高于B组（46．7±4．0）％；住院期间MACE发生率A组（6．0％）显著低于B组（25．0％），差异均有显著性意义，P＜0．05。影响MACE的Logistic多因素回归分析进入回归方程的有ΣSTR、发病至IRA再通时间、糖尿病史，ΣSTR贡献最大。结论急性STEMI患者直接PCI后心电图相关导联ST段的早期回落对PCI后的近期预后有重要的独立预测作用。
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