目的:研究高危再次剖宫产出血孕妇预防性应用欣母沛宫体注射的效果、不良反应及对术后泌乳功能的影响.方法:收集2014年1月~2015年12月我院妇产科住院高危再次剖宫产产妇68例,按照随机数字表法分为两组:对照组34例剖宫产术中予以缩宫素经宫体注射和静脉滴注+米索前列醇纳肛,观察组34例在对照组的基础上,加用欣母沛经宫体注射,对比两组的产后出血量、产后出血发生率、泌乳功能及药物不良反应.结果:研究组的术中、产后2h及产后24h出血量均显著低于对照组;研究组的止血时间为(19.12±9.95min)显著短于对照组的(39.85±12.34min);研究组的产后出血及输血率(11.76%、5.88%),显著低于对照组(35.29%、23.53%);研究组的子宫切除率(0.00%)显著低于对照组(2.94%);产后24h、48h,研究组的PRL水平显著高于对照组;研究组的泌乳始动时间显著短于对照组明显缩短;产后24h、48h时,观察组的泌乳量评分均显著高于对照组;研究组与对照组的不良反应比较差异无统计学意义.结论:欣母沛宫体注射能够有效减少高危再次剖宫产出血,改善泌乳功能,且不良反应较少,值得推广应用.%Objective To study the prophylactic use of hin pregnant women at high risk of cesarean section hemorrhage again mother repeatedly from the injection effect, adverse reaction and the effect of postoperative mammary function. Meth-ods collected from January 2014 to December 2014, 68 cases of maternal hospital obstetrics and gynecology hospital high-risk again cesarean delivery, according to random number table method is divided into two groups: the control group of 34 cases of cesarean section of oxytocin from injection and intravenous drip + anus misoprostol, 34 cases in the control group, on the basis of the observation group added with hin mother repeatedly from the injection, compared two groups of postpartum haemor-rhage amount, the incidence of postpartum hemorrhage, lactation function and adverse drug reactions. Results the intraop-erative, postpartum team 2 h and 24 h postpartum haemorrhage amount were significantly lower than the control group; Team the bleeding time was(19.12 + / - 9.95 min)significantly shorter than the control group(39.85 + / - 12.34 min); The team of postpartum bleeding and blood transfusion rate(11.76%, 5.88%), significantly lower than the control group(35.29%, 23.53%);Team's uterus resection(0.00%)was significantly lower than the control group(2.94%); After 24 h, 48 h, the team of PRL level is significantly higher than the control group; Team's lactation initiating time was significantly shorter than the control group significantly shortened; 24 h, 48 h, postpartum lactation quantity score in observation group were significantly higher than that of control group; The team there was no statistically significant difference compared with control group the adverse reactions of. Conclusion xin pei from injection can effectively reduce high-risk cesarean section hemorrhage again, to improve the function of lactation, and less adverse reactions, is worthy of popularization and application.
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