目的:总结暴发性心肌炎的临床特征与治疗.方法:对我院1997年6月~2014年8月收治的22例暴发性心肌炎儿童的临床资料进行回顾性分析.结果:22例中男11例,女11例;年龄2天~18岁,平均年龄8.96岁.患儿临床表现不典型,多以心外表现为首发症状,入院时误诊14例(63.6%).确诊后19例予以大剂量糖皮质激素;11例同时予以大剂量丙种球蛋白(IVIG)等治疗,其中9例痊愈,2例死亡.22例中最后13例治愈,6例死亡,3例放弃治疗.结论:暴发性心肌炎临床缺乏特征性,早期易于误诊.应用大剂量糖皮质激素和IVIG等综合治疗有助于提高抢救成功率.%Objective To explore the clinical characteristics and treatment of fulminant myocarditis (FMC) in children. Methods The data of 22 children with fulminant myocarditis hospitalized in the Third Xiangya Hospital of Central South Uni-versity from June 1996 to August 2014 were analyzed retrospectively. Results 22 cases included 11male and 11female cases, aged from 2 days after birth to 18 years old (average age was 8.96 years old). The clinical manifestation of the patients diagnosed with FMCwere atypical. The earliest symptoms in most of the patients werenon cardiac manifestations, and 14 cases were mis-diagnosed at admission (63.6%). After diagnosis, 19 cases were treated with high dose of glucocorticoid. At the same time, 11 cases treated with large dose of gamma globulin (IVIG). Among them, 9 cases were cured, 2 cases died. In the total 22 cases, 13 were cured, 6 died and 3 were abandoned. Conclusion The clinical manifestations of the patients with FMC are atypical, and whichease tobe misdiagnosed in the early phase of the disease. Combined treatment with high dose of glucocorticoid and IVIG can help to improve the rescue rate.
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