Objective To observe the clinical efficacy of photodynamic treatment with pingyangmycinum for condyloma acuminatum. Methods 90 patients with Condyloma acuminatum were randomly divided into observation group and control group(control group 1 and control group 2). Results There were markedly effective 19 cases(63.3%), effective 10 cases(33.3%)and invalid 1 case(3.3%), the total effective 63 cases(96.7%); control group, markedly effective 15 cases(50.0%)and effective 9 cases(30.0%), invalid 6 cases（20.0%）, total 24 cases(80.0%); control group, markedly effective 13 cases(43.3%), effective 10 cases(33.3%), invalid 7 cases（23.3%）, total effective 23 cases（76.7%）. The total efficiency of observation group was significantly higher than that of control group 1 and control group 2(P＜0.05); compared with the efficiency of observation group and control group, the difference was statistically significant(P <0.05);The inefficiency of the observation group and control group 1 and 2 was statistically significant(P <0.05). There were 1 case of recurrence in observation group（3.3%）,4 cases of recurrence in control group 1(13.3%) and 3 cases of recurrence in control group 2(10.0%). Conclusion Photodynamic combined with Pingyangmycinum in the local block therapy of condyloma acuminatum is more effective,which can reduce the recurrence rate effectively,and worthy of clinical application.%目的 观察光动力联合平阳霉素局封治疗尖锐湿疣的临床疗效.方法 将90例尖锐湿疣患者随机分为观察组和对照组(对照组1和对照组2).比较两组患者治疗后的总有效率和复发率.结果 观察组显效19例(63.3%),有效10例(33.3%),无效1例(3.3%),总有效29例(96.7%);对照组1显效15例(50.0%),有效9例(30.0%),无效6例(20.0%),总有效24例(80.0%);对照组2显效13例(43.3%),有效10例(33.3%),无效7例(23.3%),总有效23例(76.7%).观察组总有效率显著高于对照组1和对照组2,具有统计学意义(P＜0.05);观察组显效率与对照组2比较,差异有统计学意义(P＜0.05);观察组与对照组1、2的无效率比较有统计学意义(P＜0.05).观察组复发率1例(3.3%),对照组1复发率4例(13.3%),对照组2复发率3例(10.0%).结论 光动力联合平阳霉素局封治疗较单联用法更有效,并能有效的降低复发率,值得临床推广使用.
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