首页> 中文期刊> 《分析测试学报》 >离子富集脉冲电源对提高飞行时间质谱仪灵敏度的影响

离子富集脉冲电源对提高飞行时间质谱仪灵敏度的影响

         

摘要

研究自制离子富集脉冲电源对飞行时间质谱仪灵敏度的提高效果。离子富集脉冲电源包括脉冲信号产生模块、放大隔离模块、开关驱动模块、高压电路模块和负载阻抗匹配模块,输出一路中压脉冲信号,两路对称高压脉冲信号。利用自制电喷雾电离源及激光解析电离源与飞行时间质谱仪联用,调试中压脉冲信号。结果显示,应用离子富集脉冲电源后仪器对不同样品的检测灵敏度可提高6~24倍。%The effect of sensitivity enhancement of time-of-flight mass spectrometer( TOF MS)was studied with home-made ion enrichment pulse power. lon enrichment pulse power includes pulse sig-nal generating module,amplification and isolation module,switching driving module,high voltage circuit module and load impedance matching module,outputing one medium voltage pulse signal and two-way symmetric high voltage pulse signals. ln this work,TOF MS with electrospray ionization ( ESl)was combined with laser desorption ionization( LDl)to debug ion enrichment pulse power. As a conclusion,the detection sensitivity of the instrument could be increased by 6-24 times for differ-ent samples when applying ion enrichment pulse power.

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