椎间盘源性疼痛的机制及其治疗是近年来的研究热点之一.研究表明疼痛的发生涉及到椎间盘变性、神经纤维的异常增殖、生物化学因素,甚至包括生理、情绪以及遗传因素的影响;有关椎间盘源性疼痛的治疗,除了保守治疗及传统的外科手术外,各种经皮微创介入技术因其操作简单,创伤小,并发症少,术后恢复期短等优势,已在临床上广泛应用.此外,各种新型的治疗方法目前也逐渐发展起来,但是其临床疗效尚需进一步的研究加以证实.%The mechanism and treatment of discogenic pain has been one of the hot research topics in recent years. Many studies have indicated that discogenic pain is closely associated with the degeneration of disc, abnormal proliferation of nerve fibers, some biological chemical factors, etc. Even physiological, emotional and genetic factors can affect the pain severity. In respect of its treatment, besides conservative measures and traditional surgery, there are many kinds of percutaneous minimally - invasive interventional techniques, which have been widely employed in clinical practice nowadays as these operations are simply-manipulated and minimally - invasive with fewer complications. Moreover, lots of kinds of new therapies for discogenic pain have gradually developed, although their clinical effects need to be confirmed with more studies.
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