Objective To study the changes and clinical significance of serum LTE4 and T - IgE in asthma children. Methods The serum LTE4 and T - IgE level in 39 asthma children were detected by ELISA method. The results were compared with those of the healthy control children. Results The serum LTE4 and T - IgE of asthma children in acute attack stage was significantly higher than that of the controls(P < 0.01) . The discrepancy was significant in statistics. Conclusion LTE4 ,T - IgE takes part in the attack process of the asthma.%目的 探讨哮喘急性期患儿血清LTE4和总IgE水平的变化及临床意义.方法 采用ELISA法检测39例哮喘患儿及19例健康儿童的血清LTE4和总IgE(T- IgE)水平,并进行比较.结果 哮喘组的血清LTE4及T- IgE水平明显升高,与正常对照组相比(P＜0.01),差异有统计学意义.结论 LTE4、T- IgE参与了哮喘的发病过程.
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