Autoclave is a major process to inactivate Aspergillus niger spores. The specific heat death constants and activation energy of A. niger spores were calculated through study on different temperature during the autoclave. The results showed that specific heat death constants at 97,115,121 ℃ were 0. 028 39,0. 041 59,0. 065 92 / min re-spectively,and the activation energy was 38 324. 479 4 J/ mol. These results provided theoretical base to use autoclave to inactivate A. niger spores in large scale.%高温高压灭菌是黑曲霉孢子灭活的主要方式。通过研究黑曲霉孢子在高温高压过程中的死亡率，计算黑曲霉孢子的比热死速率常数和活化能。结果表明，黑曲霉孢子在97、115、121℃时的比热死速率常数分别为0.02839、0.04159、0.06592/ min，热死的活化能为38324.4794 J/ mol。为利用高温高压灭活大量曲霉孢子提供了理论基础。
展开▼
