目的：调查晚期癌症患者营养不良的发生情况，比较肠内营养（EN）及肠外营养（PN）支持的疗效。方法：随机选取188例住院晚期癌症患者，用营养风险筛查2002（NRS2002）量表评估患者营养状况。将诊断为营养不良的患者随机分为2组，分别给予肠内营养和肠外营养支持，观察并比较两组患者治疗前后的营养改善情况、生存质量及功能康复状况。结果：患者营养不良发生率为60．1％，≥70岁者发生率高于＜70岁者（P ＜0．05）；两组治疗前后的营养状况指标、生存质量评分和功能康复评分均有统计学差异（P ＜0．05），治疗后 EN 组营养状况指标、生存质量指标和功能康复指标均优于 PN 组（P ＜0．05）。结论：晚期癌症患者营养不良发生率高，在胃肠道功能正常时首选肠内营养支持治疗。%Objective:To investigate the prevalence of malnutrition and explore the effects of two nutritional sup-ports in terminal cancer patients.Methods:All 188 terminal cancer patients were selected to investigate the preva-lence of malnutrition by NRS2002.Patients with a diagnosis of malnutrition were divided into 2 groups randomly and accepted EN and PN supports respectively,2 weeks later,related indexes were determined including nutritional status, quality of life and functional rehabilitation.Results:The average prevalence of malnutrition was 60.1% prevalence in patients over 70 years old was significantly higher than it in below 70 years old(P <0.05).There was significant difference of related indexes between pre -treatment and post -treatment in both groups(EN and PN group).Related indexes in EN group was significantly superior to those in PN group(P <0.05).Conclusion:There is a high preva-lence of malnutrition in terminal cancer patients,and it is essential to nutritional support.The first choice of nutritional support is eternal nutrition if patients own normal digestive and absorptive functions.
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