Objective To investigate the effect of preoperative single femoral nerve block on postoperative analgesia in elderly patients undergoing total knee arthroplasty.Methods Forty elderly patients scheduled for unilateral knee replacement surgery under general anesthesia were randomly divided into control group(group C)and femoral nerve block group(group F),with 20 patients in each group.All patients underwent endotracheal general anesthesia.Patients in group F were given nerve stimulator-guided femoral nerve block before anesthesia induction with 20 mL of 0.5% ropivacaine.Patients in group C received no treatment.After operation,patients received patient-controlled intravenous analgesia(PCIA)with sufentanil,and VAS score ≤ 3 was main-tained.If VAS score>3,patients were injected with flurbiprofen axetil.The comfort level was e-valuated with Bruggrmann comfort scale(BCS)at 2,4,8,12,24 and 48 hours after operation.The consumption of sufentanil,frequency of patient-controlled analgesia,usage rate of flurbiprofen ax-etil and incidence of adverse reactions were recorded within 24 hours after operation.Results Compared with group C,femoral nerve block increased the comfort level and decreased the con-sumption of sufentanil,frequency of patient-controlled analgesia and usage rate of flurbiprofen ax-etil(P <0.05).There was no significant difference in the incidence of postoperative adverse reac-tions between the two groups(P >0.05).Conclusion Preoperative single femoral nerve block can improve postoperative analgesic efficacy and reduce the consumption of opioid analgesics in elderly patients undergoing total knee arthroplasty.%目的：探讨术前单次股神经阻滞对老年膝关节置换术患者术后镇痛的效果。方法选择择期拟在全身麻醉下行单侧膝关节置换术老年患者40例，采用随机数字表法将患者分为对照组（C 组）和股神经阻滞组（F 组），每组20例。2组患者均选择气管插管全身麻醉。F 组于麻醉诱导前在神经刺激器引导下行患侧股神经阻滞，单次给予0．5％罗哌卡因20 mL，C 组不给予任何处理。术毕均使用舒芬太尼自控静脉镇痛，维持 VAS 评分≤3分，当VAS 评分＞3分时，静脉注射氟比洛芬酯。分别于术后2、4、8、12、24和48 h 时行 BCS 舒适度评分，记录患者术后24 h 舒芬太尼用量、自控镇痛次数、氟比洛芬酯使用率及术后不良反应发生情况。结果与 C 组比较，F 组患者术后各时点 BCS 舒适度评分均显著升高，术后24 h 舒芬太尼用量、自控镇痛次数及氟比洛芬酯使用率均显著减少（P ＜0．05）；2组不良反应发生率比较差异无统计学意义（P ＞0．05）。结论术前单次股神经阻滞可提高全身麻醉下老年膝关节置换术患者术后镇痛效果，减少术后阿片类镇痛药的用量。
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